Pharmacokinetics of spironolactone in children up to 2 years of age
Project's status: Finished
Aims of the study are to describe PK profile of spironolactoen and its main metabolites in children up to two years of age with cardiac failure, ascites and/or oedema. 27 children from neonates to 2 years old was included.
EUDRA-CT
2013-001189-40
Funding
ETF
Partners
Department of Cardiothoracic Surgery of Tartu University Clinic, Tartu, Estonia;
Pediatric and Neonatal Intensive Care Unit (PICU) of Tartu University Clinic of Anesthesiology and Intensive Care, Tartu, Estonia;
Neonatal Ward of Tartu University Children’s Clinic, Tartu, Estonia;
Hematology-Oncology Clinic, Department of radiotherapy and oncological therapy, Tartu, Estonia;
Hospital Pharmacy, Tartu University Hospital, Tartu, Estonia;
Institute of Chemistry, University of Tartu, Testing Centre, Faculty of Science and Technology, Tartu, Estonia;
United Laboratories of Tartu University Hospital, Tartu University Hospital, Tartu, Estonia.