ESNEE

ESNEE project aimed to provide an integrated assessment of exposure among neonates in Europe to potentially toxic excipients.
Main objectives:

• to undertake a comprehensive European questionnaire and point prevalence study of excipient exposure in neonates; 
• to conduct a systematic review 
• to develop EK models for selected excipients Observational case-controlled study. 

Primary outcome measures: To develop pilot excipient kinetic models to indicate how much of each selected excipient is in the bloodstream of babies who have been given medicines containing those excipients.